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Department |
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Work Area & Experience |
More than 10 years research experience in Medicinal Chemistry with main emphasis on natural product chemistry. We are involve in drug development and new formulations from medicinal plants.
Previous experiences:
1. Project Assistant-II, CSIR-CDRI, Lucknow (Mar 2010 to Jul 2012)
2. Junior Research Fellow, CSIR-CDRI, Lucknow (Jul 2012 to Jun 2014).
3. Senior Research Fellow, CSIR-CDRI, Lucknow (Jul 2014 to Jan 2017)
4. Research Scientist-II, Jubilant Biosys Ltd, Noida, India (Mar 2017 to Feb 2019)
5. Postdoctoral Research Fellow, Yunnan University, Kunming, China (Mar 2019 to Nov 2019).
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Current Area of Interest |
Natural Product Chemistry, Medicinal Chemistry
For more details please visit:
https://sites.google.com/view/kapilslab/home
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Qualification |
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Publications |
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Pandey, J.; Dev, K.; Chattopadhyay, S.; Kadan, S.; Sharma, T.; Sanyal, S.; Siddiqi, M. I.; Zaid, I.; & Tamrakar, A.. 2021. ß-Sitosterol-D-Glucopyranoside Mimics Estrogenic Properties and Stimulates Glucose Utilization in Skeletal Muscle Cells Molecules 26(11), 3129
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Trivedi, R.; Adhikary, S.; Kothari, P.; Ahmad, N.; Mittapelly, N.; Pandey, G.; Shukla, M.; Kumar, S.; Dev, K.; Choudhary, D.; Maurya, R.; Lal, J.; Mishra, P. R.. 2020. Self-emulsifying formulation of Spinacia oleracea reduces the dose and escalates bioavailability of bioactive compounds to accelerate fracture repair in rats Clinical Phytoscience 6, 2-15
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Choudhary, D.; Kothari, P.; Tripathi, A. K.; Singh, S.; Adhikary, S.; Ahmad, N.; Kumar, S.; Dev, K.; Mishra, V. K.; Shukla, S.; Maurya, R.; Mishra, P. R.; Trivedi, R.. 2018. Spinacia oleracea extract attenuates disease progression and sub-chondral bone changes in monosodium iodoacetate induced osteoarthritis in rats Bmc Complementary And Alternative Medicine, 18, 1-16
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Kumar, P.; Kushwaha, P.; Ahmad, N.; Maurya, S. W.; Dev, K.; Khedgikar, V.; Siddiqui, I. R.; Trivedi, R. and Maurya, R.. 2017. Design and synthesis of dalbergin analogues and the evaluation of anti-osteoporotic activity Bioorganic & Medicinal Chemistry Letters, 27, 1765-1775.
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Porwal, K.; Pal, S.; Dev, K.; China, S. P.; Kumar, Y.; Singh, C.; Barbhuyan, T.; Sinha, N.; Sanyal, S.; Trivedi, A. K.; Maurya, R. and Chattopadhyay, N.. 2017. Guava fruit extract and its triterpene constituents have osteoanabolic effect: stimulation of osteoblast differentiation by activation of mitochondrial respiration via the Wnt/ß-catenin signalling The Journal Of Nutritional Biochemistry, 44, 22-34
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Adhikary, S.; Choudhary, D.; Ahmad, N.; Kumar, S.; Dev, K.; Mittapelly, N.; Pandey, G.; Mishra, P. R.; Maurya, R.; Trivedi, R.,. 2017. Dried and free flowing granules of Spinacia oleracea accelerate bone regeneration and alleviate post-menopausal osteoporosis Menopause, 24, 686-698
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Gautam, J.; Khedgikar, V.; Kushwaha, P.; Choudhary, D.; Nagar, G. K.; Dev, K.; Dixit, P.; Singh, D.; Maurya, R.; Trivedi, R.. 2017. Formononetin, an isoflavone, activates AMPK/ß-catenin signaling to inhibit adipogenesis and rescues C57BL/6 mice against high fat diet induced obesity and bone loss British Journal Of Nutrition, 117, 645-661
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Srivastava, A.; Singh, H.; Mishra, R.; Dev, K.; Tandon, P.; Maurya, R.,. 2017. Structural insights, protein-ligand interactions and spectroscopic characterization of isoformononetin Journal Of Molecular Structure, 1133, 479-491
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Singh, H.; Singh, S.; Srivastava, A.; Tandon, P.; Bharti, P.; Kumar, S.; Dev, K.; Maurya, R.. 2017. Study of hydrogen?bonding, vibrational dynamics and structure-activity relationship of genistein using spectroscopic techniques coupled with DFT Journal Of Molecular Structure 1133, 929-939
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Mittal, M.; Pal, S.; China, S. P.; Porwal, K.; Dev, K.; Shrivastava, R.; Raju, K. S.; Rashid, M.; Trivedi, A. K.; Sanyal, S.; Wahajuddin, M.; Bhaduria, S.; Maurya, R.; Chattopadhyay, N.. 2017. Pharmacological activation of aldehyde dehydrogenase 2 promotes osteoblast differentiation via bone morphogenetic protein-2 and induces bone anabolic effect Toxicology And Applied Pharmacology 316, 63-73
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Mansoori, M. N.; Tyagi, A. M.; Shukla, P.; Srivastava, K.; Dev, K.; Chillara, R.; Maurya, R.; Singh, D.. 2016. Methoxy isoflavone formononetin and isoformononetin inhibit the differentiation of Th17 cells and B-cell lymphopoesis to promote osteogenesis in estrogen-deficient bone loss conditions Menopause, 23, 565-576
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Srivastava, A.; Mishra, R.; Kumar, S.; Dev, K.; Tandon, P.; Maurya, R.. 2015. Molecular structure, spectral investigation (1H NMR, 13C NMR, UV–Visible, FT-IR, FT-Raman), NBO, intramolecular hydrogen bonding, chemical reactivity and first hyperpolarizability analysis of formononetin [7-hydroxy-3(4-methoxyphenyl)chromone]: A quantum chemical study Journal Of Molecular Structure, 1084, 55-73
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Taneja, I.; Raju, K. S. R.; Mittal, M.; Dev, K.; Khan, M. F.; Maurya, R.; Wahajuddin, M.. 2015. Bioavailability, plasma protein binding and metabolic stability studies of ALDH2 activator, alda-1, using validated LC-ESI-MS/MS method in rat plasma Rsc Advances, 5, 54395- 54402.
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Omeje, E. O.; Khan, M. P.; Osadebe, P. O.; Tewari, D.; Khan, M. F.; Dev, K.; Maurya, R. and Chattopadhyay, N.. 2014. Analysis of constituents of the eastern Nigeria mistletoe, Loranthus micranthus Linn revealed presence of new classes of osteogenic compounds. Journal Of Ethnopharmacology, 151, 643-651
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